Description

(2β)-Methyl Megestrol Acetate CAS NO 907193-65-1 is a high-purity synthetic steroid derivative, specifically a methylated analog of megestrol acetate. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key intermediate or active pharmaceutical ingredient (API) in specialized therapeutic areas. It is primarily sought by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of novel hormonal therapies, oncology treatments, and other specialized medicinal products.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel progestin and anti-cancer drug candidates.
• Research & Development: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) of steroid hormones.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation of related compounds.
• API Synthesis: Potential use in the controlled synthesis of active pharmaceutical ingredients for hormonal regulation therapies.
• Preclinical Studies: Utilized in animal model research for evaluating the efficacy and pharmacokinetics of new therapeutic agents.

Basic Information

Product Name	(2β)-Methyl Megestrol Acetate
CAS No.	907193-65-1
Molecular Formula	C25H34O4
Molecular Weight	398.54 g/mol
Synonyms	2β-Methylmegestrol Acetate; 17α-Acetoxy-6-methyl-2β-methylpregna-4,6-diene-3,20-dione; Megestrol Acetate 2β-Methyl Derivative; 2β-Methyl-17α-acetoxy-6-methylpregna-4,6-diene-3,20-dione; (8R,9S,10R,13S,14S,17R)-17-acetyl-2,10,13-trimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl acetate
EINECS	Contact for details

Quality Control

Our (2β)-Methyl Megestrol Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.