Description

1-(4-Chlorophenyl)-2,2,2-Trifluoroethyl 4-Methylbenzenesulfonate is a specialized organic intermediate featuring a unique trifluoroethyl tosylate moiety. This compound matters for its role as a versatile building block in advanced synthetic chemistry, enabling the introduction of fluorinated and aryl-functionalized groups. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in CNS and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique surface properties.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for catalytic systems in asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable reagent for academic and industrial research exploring new fluorination methodologies and reaction mechanisms.

Basic Information

Product Name	1-(4-Chlorophenyl)-2,2,2-Trifluoroethyl 4-Methylbenzenesulfonate
CAS No.	907175-73-9
Molecular Formula	C15H12ClF3O3S
Molecular Weight	364.76 g/mol
Synonyms	1-(4-Chlorophenyl)-2,2,2-trifluoroethyl p-toluenesulfonate; 4-Chloro-α-(trifluoromethyl)benzyl tosylate; p-Chloro-α-(trifluoromethyl)benzyl tosylate; (4-Chlorophenyl)(trifluoromethyl)methyl 4-methylbenzenesulfonate; Tosylate of 1-(4-chlorophenyl)-2,2,2-trifluoroethanol; α-(Trifluoromethyl)-4-chlorobenzyl tosylate
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-2,2,2-Trifluoroethyl 4-Methylbenzenesulfonate undergoes rigorous quality testing to ensure compliance with industry standards for research and process development. We implement strict in-process controls and final release testing, including identity confirmation and purity verification via chromatographic methods. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.