Description

(2S)-1-[1-[(4-Chloro-2-Fluorophenyl)Methyl]-4-Piperidinyl]-2-Ethylpiperazine is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry critical for modern drug development. This compound is valued for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where precise molecular structure and consistent quality are paramount for successful clinical outcomes.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Neurological Research: Used in the development of drug candidates targeting receptors in the central nervous system.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in scale-up and route development for the commercial manufacturing of complex drug molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and development projects.
• Reference Standard: Used as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	(2S)-1-[1-[(4-Chloro-2-Fluorophenyl)Methyl]-4-Piperidinyl]-2-Ethylpiperazine
CAS No.	906815-95-0
Molecular Formula	C18H27ClFN3
Molecular Weight	339.88 g/mol
Synonyms	(2S)-1-[1-[(4-Chloro-2-fluorophenyl)methyl]piperidin-4-yl]-2-ethylpiperazine; 1-(1-[(4-Chloro-2-fluorophenyl)methyl]-4-piperidinyl)-2-ethyl-(2S)-piperazine; (S)-1-(1-((4-Chloro-2-fluorobenzyl))-4-piperidyl)-2-ethylpiperazine; UNII-8X7S488Q0W; 8X7S488Q0W; 906815-95-0; (2S)-2-Ethyl-1-[1-[(4-chloro-2-fluorophenyl)methyl]-4-piperidinyl]piperazine
EINECS	Contact for details

Quality Control

Our (2S)-1-[1-[(4-Chloro-2-Fluorophenyl)Methyl]-4-Piperidinyl]-2-Ethylpiperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC to confirm stereochemical purity and identity confirmation by spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and other critical parameters to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.