Description

1-Boc-4-Cyano-4-(3,4-Difluorophenyl)-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine core. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for the development of novel pharmaceutical compounds, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Preclinical Development: Employed in the scale-up synthesis of candidate drugs for toxicological and pharmacological evaluation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for clients.
• Process Chemistry: Used in route scouting and development for the efficient, large-scale manufacturing of complex target molecules.

Basic Information

Product Name	1-Boc-4-Cyano-4-(3,4-Difluorophenyl)-Piperidine
CAS No.	906369-56-0
Molecular Formula	C17H20F2N2O2
Molecular Weight	322.35 g/mol
Synonyms	1-Boc-4-cyano-4-(3,4-difluorophenyl)piperidine; tert-Butyl 4-cyano-4-(3,4-difluorophenyl)piperidine-1-carboxylate; 4-Cyano-4-(3,4-difluorophenyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-cyano-4-(3,4-difluorophenyl)piperidine; 4-(3,4-Difluorophenyl)-4-cyanopiperidine-1-carboxylic acid tert-butyl ester; BOC-4-Cyano-4-(3,4-Difluorophenyl)Piperidine; 906369-56-0
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Cyano-4-(3,4-Difluorophenyl)-Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.