Description

tert-Butyl 4-Carbamoyl-4-(4-Fluorobenzyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with a fluorobenzyl substituent and a protected amine. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of novel drug candidates, especially in medicinal chemistry programs.
• CNS Drug Research: Used in the synthesis of potential therapeutics targeting neurological disorders, leveraging its piperidine scaffold.
• Oncology Drug Development: Employed as a precursor in the creation of targeted cancer therapies and kinase inhibitors.
• Protease Inhibitor Synthesis: Applicable in the construction of molecules designed to inhibit specific enzymes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.
• Chemical Biology & Proteomics: Utilized as a tool compound or a tagged molecule for studying biological pathways and protein interactions.

Basic Information

Product Name	tert-Butyl 4-Carbamoyl-4-(4-Fluorobenzyl)Piperidine-1-Carboxylate
CAS No.	906329-65-5
Molecular Formula	C18H25FN2O3
Molecular Weight	336.41 g/mol
Synonyms	1-Boc-4-Carbamoyl-4-(4-Fluorobenzyl)Piperidine; 4-(Aminocarbonyl)-4-[(4-fluorophenyl)methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 4-Carbamoyl-4-(4-fluorobenzyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(aminocarbonyl)-4-[(4-fluorophenyl)methyl]-1-piperidinecarboxylate; 1-tert-Butoxycarbonyl-4-carbamoyl-4-(4-fluorobenzyl)piperidine; 4-(4-Fluorobenzyl)-4-(aminocarbonyl)piperidine-1-carboxylic acid tert-butyl ester; BOC-4-Carbamoyl-4-(4-Fluorobenzyl)Piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Carbamoyl-4-(4-Fluorobenzyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.