Description

(S)-2-Formamido-3-(4-Hydroxy-3,5-Diiodophenyl)Propanoic Acid is a high-purity, non-natural amino acid derivative characterized by its chiral center and halogenated aromatic ring. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutics, including thyroid hormone analogs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a precursor or reference standard in metabolic pathway studies and enzyme inhibition research.
• Peptide Synthesis: Incorporation into custom peptides to study structure-activity relationships (SAR) due to its iodinated phenolic side chain.
• Thyroid Hormone Analog Development: Serves as a core structural motif in the research and development of thyroid receptor ligands.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions and other synthetic transformations to create complex, iodinated aromatic compounds.
• Diagnostic Agent Precursor: Potential intermediate in the synthesis of contrast agents or radioligands for imaging applications.

Basic Information

Item	Detail
Product Name	(S)-2-Formamido-3-(4-Hydroxy-3,5-Diiodophenyl)Propanoic Acid
CAS No.	906327-16-0
Molecular Formula	C10H9I2NO4
Molecular Weight	460.99 g/mol
Synonyms	D-3-(4-Hydroxy-3,5-diiodophenyl)-2-formamidopropanoic Acid; (S)-3-(4-Hydroxy-3,5-diiodophenyl)-2-formamidopropanoic Acid; L-3-(4-Hydroxy-3,5-diiodophenyl)-2-formamidopropanoic Acid (incorrect stereochemistry); 2-Formamido-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid; Formamido-diiodotyrosine derivative; 906327-16-0; (S)-Formamido-DIT
EINECS	Contact for details

Quality Control

Our (S)-2-Formamido-3-(4-Hydroxy-3,5-Diiodophenyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.