Description

3-Quinolinecarboxylic Acid, 1-(6-Amino-3,5-Difluoro-2-Pyridinyl)-8-Chloro-6,7-Difluoro-1,4-Dihydro-4-Oxo-, Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical to enable the synthesis of complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of next-generation fluoroquinolone antibiotics and other therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for research into new antibacterial, antiviral, or anticancer compounds.
• Chemical Research & Development: Used in academic and industrial labs to explore novel heterocyclic chemistry and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various applications.
• Process Chemistry & Scale-Up: A key material for optimizing synthetic routes from laboratory to pilot and commercial production scales.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-(6-Amino-3,5-Difluoro-2-Pyridinyl)-8-Chloro-6,7-Difluoro-1,4-Dihydro-4-Oxo-, Ethyl Ester
CAS No.	906088-96-8
Molecular Formula	C₁₇H₁₀ClF₄N₃O₃
Molecular Weight	415.73 g/mol
Synonyms	1-(6-Amino-3,5-difluoropyridin-2-yl)-8-chloro-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; Ethyl 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate; 906088-96-8; ABT-492 intermediate; Zabofloxacin intermediate; DW-224a intermediate; Quinolone carboxylic acid ester derivative
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.