Description

Piperidin-3-Ylmethyl Trifluoromethanesulfonate is a high-purity triflate salt derivative of a piperidine scaffold, serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in constructing complex nitrogen-containing molecules, particularly in pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working in drug discovery, agrochemicals, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to introduce the piperidinylmethyl moiety into novel drug candidates.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and herbicides that require specific nitrogen heterocycles.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	Piperidin-3-Ylmethyl Trifluoromethanesulfonate
CAS No.	906073-55-0
Molecular Formula	C8H14F3NO3S
Molecular Weight	261.26 g/mol
Synonyms	3-(Trifluoromethanesulfonyloxymethyl)piperidine; (Piperidin-3-yl)methyl trifluoromethanesulfonate; 3-Piperidinylmethyl Triflate; Trifluoromethanesulfonic Acid Piperidin-3-Ylmethyl Ester; 1-(Trifluoromethylsulfonyloxy)methyl-3-piperidine; 906073-55-0; Piperidine-3-methanol, 1-oxide, triflate
EINECS	Contact for details

Quality Control

Our Piperidin-3-Ylmethyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.