Description

Methyl (3R)-3-Amino-3-(3-Chlorophenyl)Propanoate CAS NO 905991-90-4 is a high-purity chiral intermediate featuring a 3-chlorophenyl group and an ester-protected amino acid backbone. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals where stereochemical purity is paramount. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel therapeutic agents and specialty compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Peptidomimetics Research: Serves as a constrained amino acid analog for constructing peptide-like molecules with enhanced stability and bioavailability.
• Catalyst and Ligand Development: Employed in the preparation of chiral catalysts and ligands for asymmetric synthesis.
• Fine Chemical Production: A versatile intermediate for creating specialty chemicals with specific stereochemical requirements.
• Academic & R&D: Used in laboratory-scale research for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	Methyl (3R)-3-Amino-3-(3-Chlorophenyl)Propanoate
CAS No.	905991-90-4
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	(R)-Methyl 3-Amino-3-(3-chlorophenyl)propanoate; Methyl (R)-3-amino-3-(3-chlorophenyl)propionate; (3R)-3-Amino-3-(3-chlorophenyl)propanoic Acid Methyl Ester; (R)-3-Amino-3-(3-chlorophenyl)propionic Acid Methyl Ester; 905991-90-4; (R)-3-Amino-3-(m-chlorophenyl)propionic acid methyl ester; Methyl (3R)-3-amino-3-(3-chlorophenyl)propanoate
EINECS	Contact for details

Quality Control

Our Methyl (3R)-3-Amino-3-(3-Chlorophenyl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.