Description

trans-3-(Dimethylamino)Cyclobutan-1-Ol CAS NO 905821-42-3 is a versatile chiral cyclobutane derivative featuring both an amino and a hydroxyl functional group. This unique structure makes it a valuable and sophisticated building block in modern organic synthesis, particularly for the construction of complex pharmaceutical intermediates. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Chemical Research & Development: Employed in academic and industrial R&D for methodology development and exploring new chemical spaces.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	trans-3-(Dimethylamino)Cyclobutan-1-Ol
CAS No.	905821-42-3
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	trans-3-(N,N-Dimethylamino)cyclobutan-1-ol; (1r,3r)-3-(Dimethylamino)cyclobutan-1-ol; (1s,3s)-3-(Dimethylamino)cyclobutan-1-ol; 3-(Dimethylamino)cyclobutan-1-ol, trans-; 3-Dimethylaminocyclobutanol; trans-3-Hydroxy-N,N-dimethylcyclobutanamine; Cyclobutan-1-ol, 3-(dimethylamino)-, trans-; 905821-42-3
EINECS	Contact for details

Quality Control

Our trans-3-(Dimethylamino)Cyclobutan-1-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.