Description

trans-3-(Benzyloxy)Cyclobutanamine is a high-purity, synthetically valuable chiral amine building block. This compound is specifically designed for advanced pharmaceutical research and development, offering a critical scaffold for constructing complex molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its cyclobutane core for unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Chemical Biology Probe Synthesis: Incorporated into molecular probes for studying enzyme function and protein-protein interactions within biological systems.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers with tailored properties.

Basic Information

Product Name	trans-3-(Benzyloxy)Cyclobutanamine
CAS No.	905821-36-5
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	trans-3-(Benzyloxy)cyclobutan-1-amine; (1r,3r)-3-(Phenylmethoxy)cyclobutanamine; 3-(Benzyloxy)cyclobutanamine (trans-); Benzyl trans-3-aminocyclobutyl ether; 905821-36-5; trans-3-(Benzyloxy)-1-cyclobutanamine; 1-Amino-3-(benzyloxy)cyclobutane (trans-); Cyclobutanamine, 3-(phenylmethoxy)-, (1R,3R)-
EINECS	Contact for details

Quality Control

Our trans-3-(Benzyloxy)Cyclobutanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.