Description

2-Methyl-4-(3-Chloro)Phenyl Thiazole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct thiazole-carboxylic acid core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in research for creating specialized polymers, liquid crystals, or organic electronic materials due to its rigid thiazole structure.
• Chemical Synthesis: Employed in organic chemistry research as a versatile scaffold for further functionalization and the creation of diverse chemical libraries.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling reactions, making it useful for creating biochemical probes and diagnostic agents.

Basic Information

Product Name	2-Methyl-4-(3-Chloro)Phenyl Thiazole-5-Carboxylic Acid
CAS No.	905808-17-5
Molecular Formula	C11H8ClNO2S
Molecular Weight	253.70 g/mol
Synonyms	5-Carboxy-2-methyl-4-(3-chlorophenyl)thiazole; 4-(3-Chlorophenyl)-2-methyl-1,3-thiazole-5-carboxylic acid; 2-Methyl-4-(3-chlorophenyl)-1,3-thiazole-5-carboxylic acid; 2-Methyl-4-(m-chlorophenyl)thiazole-5-carboxylic acid; 905808-17-5; Thiazole-5-carboxylic acid, 2-methyl-4-(3-chlorophenyl)-; AKOS BRN 0978
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(3-Chloro)Phenyl Thiazole-5-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom synthesis to meet specific purity or specification requirements is available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.