Description

1,3-Dihydro-Imidazol-2-One-5-(4-Trifluoromethyl)Phenyl-4-Carboxylic Acid is a high-value, multifunctional heterocyclic building block with a carboxylic acid moiety and a trifluoromethylphenyl group. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology, central nervous system (CNS), and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing enzyme inhibitors, probes, and molecular tools due to its imidazolone core.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process optimization for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	1,3-Dihydro-Imidazol-2-One-5-(4-Trifluoromethyl)Phenyl-4-Carboxylic Acid
CAS No.	905807-52-5
Molecular Formula	C11H7F3N2O3
Molecular Weight	272.18 g/mol
Synonyms	5-(4-(Trifluoromethyl)phenyl)-1,3-dihydro-2H-imidazol-2-one-4-carboxylic acid; 4-Carboxy-5-[4-(trifluoromethyl)phenyl]-2-imidazolidinone; 2-Imidazolidinone, 4-carboxy-5-[4-(trifluoromethyl)phenyl]-; 5-(4-Trifluoromethylphenyl)-4-imidazoline-2-one-5-carboxylic acid; 4-Imidazolidinone-5-(4-trifluoromethylphenyl)-4-carboxylic acid; CAS 905807-52-5
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-Imidazol-2-One-5-(4-Trifluoromethyl)Phenyl-4-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical and agrochemical R&D. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.