Description

Cefathiamidine Lactone is a key pharmaceutical intermediate in the synthesis of advanced cephalosporin antibiotics. This high-purity compound is critical for ensuring the efficacy and safety of the final active pharmaceutical ingredient (API). It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of Cefathiamidine and related cephalosporin antibiotics.
• API Manufacturing: Used in the controlled production of the final Active Pharmaceutical Ingredient for injectable formulations.
• Research & Development: Employed in medicinal chemistry for the design and development of novel β-lactam antibiotic candidates.
• Process Chemistry: Integral to scale-up and optimization studies for efficient commercial antibiotic production.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Cefathiamidine Lactone
CAS No.	905712-22-3
Molecular Formula	C20H24N6O6S2
Molecular Weight	508.57 g/mol
Synonyms	(6R,7R)-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Lactone; Cefathiamidine Impurity; Cefathiamidine Related Compound A; Cefathiamidine δ-Lactone; Antibiotic 8000 Lactone; 7-ACA Derivative Lactone
EINECS	Contact for details

Quality Control

Our Cefathiamidine Lactone is manufactured under strict quality management systems to meet the exacting standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR. Certificates of Analysis (COA) documenting full compliance with agreed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.