Description

(4As,6R,7S,7Ar)-6-[4-[[(1S)-2,3-Dihydro-1H-Inden-1-Yl]Amino]-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl]Hexahydro-2-(4-Methoxyphenyl)-Cyclopenta-1,3-Dioxin-7-Ol is a sophisticated chiral intermediate or active pharmaceutical ingredient (API) characterized by its complex, multi-ring structure. This compound is of significant value in pharmaceutical research and development, particularly for its potential role as a key building block in the synthesis of targeted therapeutics. It is primarily needed by R&D laboratories, process chemists, and manufacturers in the pharmaceutical and biotechnology industries engaged in developing novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of novel drug candidates, particularly in oncology and other therapeutic areas.
• Process Chemistry & Scale-Up: Used in route development, optimization, and the production of Active Pharmaceutical Ingredients (APIs) for clinical trials and commercial manufacturing.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize the biological activity of lead compounds.
• Reference Standard: Acts as a high-purity analytical standard for method development, quality control, and regulatory submissions.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biological target identification and validation studies.

Basic Information

Item	Detail
Product Name	(4As,6R,7S,7Ar)-6-[4-[[(1S)-2,3-Dihydro-1H-Inden-1-Yl]Amino]-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl]Hexahydro-2-(4-Methoxyphenyl)-Cyclopenta-1,3-Dioxin-7-Ol
CAS No.	905580-87-2
Molecular Formula	C29H30N4O4
Molecular Weight	498.57 g/mol
Synonyms	6-[4-[[(1S)-2,3-Dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]hexahydro-2-(4-methoxyphenyl)cyclopenta-1,3-dioxin-7-ol; (4aR,6R,7S,7aR)-6-[4-[[(1S)-2,3-Dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]hexahydro-2-(4-methoxyphenyl)cyclopenta-1,3-dioxin-7-ol; 905580-87-2; UNII-7V2S2C9J7K; 7V2S2C9J7K; CHEMBL3186660; AKOS025147065; BDBM50389357
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development under a quality management system. Comprehensive analytical data, including HPLC purity, chiral purity, and identity confirmation (NMR, MS), is provided. Certificates of Analysis (COA) are available upon request, detailing batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.