Description

1-(5-Fluoro-2-Morpholin-4-Ylphenyl)Methanamine is a high-value pharmaceutical intermediate and building block featuring a fluorinated aromatic core linked to a morpholine and a primary amine functional group. This unique structure makes it a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate its specific pharmacophore into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• API Synthesis: Used in the research and commercial production of Active Pharmaceutical Ingredients (APIs) that require a fluorinated morpholinobenzylamine scaffold.
• Agrochemical Research: Serves as a precursor in developing new generation pesticides and herbicides, leveraging the bioactivity of the fluorine and morpholine motifs.
• Chemical Biology & Proteomics: Employed as a specialty reagent or linker in the design of chemical probes for studying biological pathways and protein function.
• Material Science: Potential monomer or additive in the synthesis of advanced polymers and functional materials with specific electronic or surface properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and contract manufacturers for custom synthesis and process development projects.

Basic Information

Product Name	1-(5-Fluoro-2-Morpholin-4-Ylphenyl)Methanamine
CAS No.	905439-34-1
Molecular Formula	C11H15FN2O
Molecular Weight	210.25 g/mol
Synonyms	(5-Fluoro-2-morpholinophenyl)methanamine; 1-(5-Fluoro-2-morpholinophenyl)methanamine; 4-[(5-Fluoro-2-aminomethyl)phenyl]morpholine; 2-(Aminomethyl)-4-fluorophenyl morpholine; 5-Fluoro-2-morpholinobenzylamine; Benzenemethanamine, 5-fluoro-2-(4-morpholinyl)-; 905439-34-1
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoro-2-Morpholin-4-Ylphenyl)Methanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and assay results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.