Description

[Cyano-(3,4,5-Trimethoxy-Phenyl)-Methyl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular scaffold. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this precise building block to ensure the integrity and efficacy of their final drug candidates, relying on its consistent quality for scalable and reproducible processes.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• API Development: Used as a critical precursor in the development and scale-up of Active Pharmaceutical Ingredients (APIs) requiring the 3,4,5-trimethoxyphenyl pharmacophore.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry: Employed in route scouting and optimization for the commercial manufacturing of complex organic molecules.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in regulatory submissions.

Basic Information

Product Name	[Cyano-(3,4,5-Trimethoxy-Phenyl)-Methyl]-Carbamic Acid tert-Butyl Ester
CAS No.	904818-28-6
Molecular Formula	C16H22N2O5
Molecular Weight	322.36 g/mol
Synonyms	tert-Butyl N-[(3,4,5-trimethoxyphenyl)(cyano)methyl]carbamate; Boc-Protected α-Amino Nitrile Derivative; (3,4,5-Trimethoxyphenyl)((tert-butoxycarbonyl)amino)acetonitrile; N-Boc-α-amino-(3,4,5-trimethoxyphenyl)acetonitrile; tert-Butyl ((cyano)(3,4,5-trimethoxyphenyl)methyl)carbamate; Carbamic acid, N-[cyano(3,4,5-trimethoxyphenyl)methyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our [Cyano-(3,4,5-Trimethoxy-Phenyl)-Methyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.