Description

8A-(4-Fluoro-Phenyl)-Octahydro-Pyrrolo[1,2-A]Pyrimidine CAS NO 904817-57-8 is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused pyrrolopyrimidine structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities (NCEs) and high-potency active pharmaceuticals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates targeting central nervous system (CNS) disorders, oncology, and antiviral therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Integral to the process development and scale-up of new active pharmaceutical ingredients, especially those with fused heterocyclic core structures.
• Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and commercial APIs under current Good Manufacturing Practice (cGMP) standards.
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays to study enzyme inhibition or receptor binding.

Basic Information

Product Name	8A-(4-Fluoro-Phenyl)-Octahydro-Pyrrolo[1,2-A]Pyrimidine
CAS No.	904817-57-8
Molecular Formula	C14H17FN2
Molecular Weight	232.30 g/mol
Synonyms	8a-(4-Fluorophenyl)octahydropyrrolo[1,2-a]pyrimidine; 8a-(4-Fluorophenyl)-1,2,3,5,6,7,8,8a-octahydropyrrolo[1,2-a]pyrimidine; Octahydro-8a-(4-fluorophenyl)pyrrolo[1,2-a]pyrimidine; Pyrrolo[1,2-a]pyrimidine, octahydro-8a-(4-fluorophenyl)-; 904817-57-8; 8A-(4-FLUORO-PHENYL)-OCTAHYDRO-PYRROLO[1,2-A]PYRIMIDINE
EINECS	Contact for details

Quality Control

Our 8A-(4-Fluoro-Phenyl)-Octahydro-Pyrrolo[1,2-A]Pyrimidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and manufacturing. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data. Specifications can be aligned with research-grade or cGMP standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize moisture uptake and exposure to air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.