Description

4-[1,2,4]Triazol-1-Ylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique triazole-piperazine hybrid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel antifungal and antiviral agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the production of specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of triazole-containing antifungal drugs and other bioactive molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic candidates.
• Process Chemistry: Serves as a crucial intermediate in the scale-up and commercial manufacturing of APIs.
• Antiviral Drug Development: Potential precursor in the synthesis of compounds targeting viral proteases or replication mechanisms.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects.
• Bioconjugation & Probe Development: The reactive functional groups make it suitable for creating chemical probes or conjugates for biological studies.

Basic Information

Product Name	4-[1,2,4]Triazol-1-Ylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	904816-91-7
Molecular Formula	C13H23N5O2
Molecular Weight	281.36 g/mol
Synonyms	1-Boc-4-((1H-1,2,4-triazol-1-yl)methyl)piperazine; tert-Butyl 4-((1H-1,2,4-triazol-1-yl)methyl)piperazine-1-carboxylate; 4-((1H-1,2,4-Triazol-1-yl)methyl)piperazine-1-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 4-[(1H-1,2,4-triazol-1-yl)methyl]-1-piperazinecarboxylate; Piperazine, 4-[(1H-1,2,4-triazol-1-yl)methyl]-, 1-(1,1-dimethylethyl) ester; BOC-Piperazine-triazole intermediate
EINECS	Contact for details

Quality Control

Our 4-[1,2,4]Triazol-1-Ylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.