Description

4-(3-Methoxy-Phenyl)-2,3-Dihydro-1H-Benzo[B][1,4]Diazepine is a high-purity, advanced pharmaceutical intermediate belonging to the benzodiazepine class of heterocyclic compounds. Its value lies in its role as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) and for medicinal chemistry research. This compound is essential for R&D and production teams in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel benzodiazepine-based drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize pharmacological properties such as potency, selectivity, and metabolic stability.
• API Development: Serves as a core scaffold for the development of new active pharmaceutical ingredients with potential anxiolytic, sedative, or other therapeutic effects.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and drug discovery methodologies.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-(3-Methoxy-Phenyl)-2,3-Dihydro-1H-Benzo[B][1,4]Diazepine
CAS No.	904815-64-1
Molecular Formula	C₁₈H₁₈N₂O
Molecular Weight	278.35 g/mol
Synonyms	4-(3-Methoxyphenyl)-2,3-dihydro-1H-1,4-benzodiazepine; 1H-1,4-Benzodiazepine, 4-(3-methoxyphenyl)-2,3-dihydro-; 4-(3-Methoxy-phenyl)-2,3-dihydro-1H-benzo[b][1,4]diazepine; Benzo[b][1,4]diazepine, 4-(3-methoxyphenyl)-2,3-dihydro-1H-; 904815-64-1
EINECS	Contact for details

Quality Control

Our 4-(3-Methoxy-Phenyl)-2,3-Dihydro-1H-Benzo[B][1,4]Diazepine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.