Description

2-Biphenyl-4-Yl-2,3,4,5-Tetrahydro-1H-Benzo[B][1,4]Diazepine is a high-purity, advanced pharmaceutical intermediate belonging to the benzodiazepine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates targeting neurological and psychiatric disorders.
• Chemical Synthesis: Serves as a versatile precursor for the development of complex heterocyclic compounds in organic chemistry.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating ligand-receptor interactions, particularly with GABA-A receptors.

Basic Information

Product Name	2-Biphenyl-4-Yl-2,3,4,5-Tetrahydro-1H-Benzo[B][1,4]Diazepine
CAS No.	904814-74-0
Molecular Formula	C23H20N2
Molecular Weight	324.42 g/mol
Synonyms	2-(Biphenyl-4-yl)-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine; 2-(4-Phenylphenyl)-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine; 904814-74-0; Benzo[b][1,4]diazepine, 2-(1,1'-biphenyl-4-yl)-2,3,4,5-tetrahydro-; 2-(4-Biphenylyl)-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine
EINECS	Contact for details

Quality Control

Our 2-Biphenyl-4-Yl-2,3,4,5-Tetrahydro-1H-Benzo[B][1,4]Diazepine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.