Description

4H-1-Benzopyran-4-One, 7,8-Difluoro- is a high-purity fluorinated chromone derivative, a key building block in advanced organic synthesis. This compound is valued for its role in modulating the biological and photophysical properties of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in fluorinated quinoline and chromone-based therapeutic agents.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the difluoro substitution can enhance bioavailability and environmental stability.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs) and other functional organic materials due to its chromone core.
• Chemical Synthesis: An essential fluorinated synthon for medicinal and combinatorial chemistry, enabling structure-activity relationship (SAR) studies.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and the exploration of new chemical entities.

Basic Information

Product Name	4H-1-Benzopyran-4-One, 7,8-Difluoro-
CAS No.	904318-80-5
Molecular Formula	C9H4F2O2
Molecular Weight	182.13 g/mol
Synonyms	7,8-Difluorochromone; 7,8-Difluoro-4H-chromen-4-one; 7,8-Difluoro-4H-1-benzopyran-4-one; 4H-Chromen-4-one, 7,8-difluoro-; 7,8-Difluoro-4-chromone; Chromone, 7,8-difluoro-
EINECS	Contact for details

Quality Control

Our 4H-1-Benzopyran-4-One, 7,8-Difluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.