Description

(1S,2S)-trans-1-Hydroxy-1,2,3,4-Tetrahydro-2-Naphthyl Benzoate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a valuable building block for the development of complex, optically active molecules. This compound is primarily sought by pharmaceutical and fine chemical research organizations for applications in asymmetric synthesis and as a precursor for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of sophisticated ligands for transition metal catalysis, enabling enantioselective transformations.
• Fine Chemical Synthesis: Serves as a critical building block for the multi-step synthesis of complex natural products and specialty chemicals.
• Academic & Industrial Research: Employed in methodological studies and process chemistry development for stereocontrolled reactions.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in regulatory submissions.

Basic Information

Product Name	(1S,2S)-trans-1-Hydroxy-1,2,3,4-Tetrahydro-2-Naphthyl Benzoate
CAS No.	904316-37-6
Molecular Formula	C₁₈H₁₈O₃
Molecular Weight	282.33 g/mol
Synonyms	(1S,2S)-1-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl benzoate; (1S,2S)-trans-1,2,3,4-Tetrahydro-1-hydroxy-2-naphthyl benzoate; Benzoic acid (1S,2S)-1,2,3,4-tetrahydro-1-hydroxy-2-naphthyl ester; (1S,2S)-THN Benzoate; (1S,2S)-Tetralol benzoate derivative; trans-(1S,2S)-1-Hydroxy-2-benzoyloxy-1,2,3,4-tetrahydronaphthalene
EINECS	Contact for details

Quality Control

Our (1S,2S)-trans-1-Hydroxy-1,2,3,4-Tetrahydro-2-Naphthyl Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.