Description

(1R,2R)-trans-2-Amino-1,2-Dihydro-1-Naphthol Hydrochloride is a chiral, enantiomerically pure organic compound that serves as a critical building block in asymmetric synthesis. Its value lies in its utility as a precursor or intermediate for the development of complex, optically active molecules, particularly in the pharmaceutical sector. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical R&D, agrochemical synthesis, and advanced material science who require reliable, stereochemically defined starting materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and cardiovascular diseases.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Specialty Chemical Production: Employed in the multistep synthesis of complex organic molecules for research and commercial applications.
• Academic and Industrial Research: A valuable tool for chemists exploring new synthetic methodologies and reaction pathways in organic chemistry.

Basic Information

Product Name	(1R,2R)-trans-2-Amino-1,2-Dihydro-1-Naphthol Hydrochloride
CAS No.	904316-35-4
Molecular Formula	C10H12ClNO
Molecular Weight	197.66 g/mol
Synonyms	(1R,2R)-2-Amino-1,2-dihydro-1-naphthol hydrochloride; (1R,2R)-1-Amino-2-hydroxy-1,2-dihydronaphthalene hydrochloride; (1R,2R)-1,2-Dihydro-1-hydroxy-2-naphthylamine hydrochloride; trans-(1R,2R)-2-Amino-1,2-dihydro-1-naphthol HCl; (1R,2R)-trans-1,2-Dihydro-2-amino-1-naphthol hydrochloride; (1R,2R)-1,2-Dihydro-2-amino-1-naphthol hydrochloride; (1R,2R)-2-Amino-1,2-dihydronaphthalen-1-ol hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,2R)-trans-2-Amino-1,2-Dihydro-1-Naphthol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical assay, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee consistent quality, batch-to-batch reproducibility, and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.