Description

3'-[(tert-Butoxycarbonyl)Amino]-1,1'-Biphenyl-4-Carboxylic Acid is a high-purity, bifunctional organic building block featuring both a protected amine and a carboxylic acid group. This compound is critical for the synthesis of complex molecules, offering precise control over molecular architecture in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams, as well as by fine chemical manufacturers, for constructing active pharmaceutical ingredients (APIs), ligands, and other sophisticated intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Peptidomimetic Synthesis: Used to incorporate biphenyl scaffolds and protected amino acid motifs into peptide analogs and mimetics.
• Agrochemical Research: Serves as a precursor for creating advanced herbicides, fungicides, and plant growth regulators with specific activity profiles.
• Material Science: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers requiring tailored aromatic structures.
• Chemical Biology Probes: Utilized for creating labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring a specific, protected biphenyl-based carboxylic acid.

Basic Information

Product Name	3'-[(tert-Butoxycarbonyl)Amino]-1,1'-Biphenyl-4-Carboxylic Acid
CAS No.	904086-02-8
Molecular Formula	C18H19NO4
Molecular Weight	313.35 g/mol
Synonyms	4'-(Boc-amino)biphenyl-4-carboxylic acid; 4'-[(tert-Butoxycarbonyl)amino][1,1'-biphenyl]-4-carboxylic acid; 3'-(Boc-Amino)-[1,1'-biphenyl]-4-carboxylic Acid; 3'-[(tert-Butoxycarbonyl)amino]-4-biphenylcarboxylic acid; 3'-(N-Boc-amino)-4-biphenylcarboxylic acid; Boc-3-Abpc-OH; BOC-3-ABPC; 904086-02-8
EINECS	Contact for details

Quality Control

Our 3'-[(tert-Butoxycarbonyl)Amino]-1,1'-Biphenyl-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and other relevant quality guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.