Description

1-(2-Cyano-4-Nitrophenyl)Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine carboxylic acid core and substituted nitrophenyl group. This compound matters for its critical role as a key building block in the synthesis of complex, biologically active molecules, offering precise structural control for research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new drug candidates, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder targets.
• Chemical Research & Development: Used as a specialized building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Potential intermediate in the development of advanced herbicides or pesticides, leveraging its nitrophenyl and cyano functional groups.
• Material Science Research: Can be utilized in the development of organic electronic materials or metal-organic frameworks (MOFs) due to its conjugated system and coordinating carboxylic acid group.
• Contract Manufacturing (CMO/CDMO): Supplied to custom synthesis organizations for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	1-(2-Cyano-4-Nitrophenyl)Piperidine-4-Carboxylic Acid
CAS No.	903863-91-2
Molecular Formula	C13H13N3O4
Molecular Weight	275.26 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(2-cyano-4-nitrophenyl)-; 1-(2-Cyano-4-nitrophenyl)isonipecotic acid; 1-(2-Cyano-4-nitrophenyl)-4-piperidinecarboxylic acid; 1-(2-Cyano-4-nitrophenyl)piperidine-4-carboxylic acid; 1-(2-Cyano-4-nitrophenyl)piperidine-4-carboxylate; Isonipecotic acid, 1-(2-cyano-4-nitrophenyl)-; 903863-91-2; 1-(2-Cyano-4-nitrophenyl)isonipecotate
EINECS	Contact for details

Quality Control

Our 1-(2-Cyano-4-Nitrophenyl)Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet rigorous customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.