Description

1-[({1-[(4-Methoxyphenyl)Sulfonyl]Piperidin-4-Yl}Carbonyl)Oxy]Pyrrolidine-2,5-Dione is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly those targeting specific enzymatic pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel active pharmaceutical ingredients (APIs) and potential therapeutic candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Protease Inhibitor Research: Used in the development of compounds targeting proteolytic enzymes, given its pyrrolidine-2,5-dione (succinimide) core structure.
• Chemical Biology Probes: Serves as a building block for creating specialized probes to study enzyme function and cellular signaling pathways.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex target molecules.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	1-[({1-[(4-Methoxyphenyl)Sulfonyl]Piperidin-4-Yl}Carbonyl)Oxy]Pyrrolidine-2,5-Dione
CAS No.	903853-23-6
Molecular Formula	C17H20N2O7S
Molecular Weight	396.42 g/mol
Synonyms	1-({[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]carbonyl}oxy)pyrrolidine-2,5-dione; 1-[[[1-[(4-Methoxyphenyl)sulfonyl]-4-piperidinyl]carbonyl]oxy]-2,5-pyrrolidinedione; Succinimide-based piperidine sulfonamide derivative; 4-Methoxybenzenesulfonamide piperidine succinimide ester; N-[(4-Methoxyphenyl)sulfonyl]piperidine-4-carboxylic acid succinimidyl ester; 903853-23-6; 1-({[1-(4-Methoxyphenyl)sulfonyl]piperidin-4-yl}carbonyl)oxy)pyrrolidine-2,5-dione
EINECS	Contact for details

Quality Control

Our 1-[({1-[(4-Methoxyphenyl)Sulfonyl]Piperidin-4-Yl}Carbonyl)Oxy]Pyrrolidine-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.