Description

(1S)-1-Aminoindane-5-Carboxylic Acid CAS NO 903630-36-4 is a high-purity, chiral indane derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its rigid, fused-ring structure and functional handles, enabling the construction of complex molecules with defined stereochemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and for constructing conformationally constrained peptide mimetics and bioactive scaffolds.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, or insecticides with enhanced efficacy and selectivity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in catalytic asymmetric reactions to introduce stereogenic centers.
• Chemical Biology: Useful for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	(1S)-1-Aminoindane-5-Carboxylic Acid
CAS No.	903630-36-4
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(1S)-1-Amino-2,3-dihydro-1H-indene-5-carboxylic acid; (S)-1-Aminoindane-5-carboxylic acid; (S)-5-Carboxy-1-aminoindane; 1-Aminoindane-5-carboxylic acid, (1S)-; (S)-AIDA; (1S)-5-Carboxy-2,3-dihydro-1H-inden-1-amine; (S)-1-Amino-5-indanecarboxylic acid
EINECS	Contact for details

Quality Control

Our (1S)-1-Aminoindane-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.