Description

(1R)-1-Aminoindane-5-Carbonitrile is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its enantiomeric purity and functionalized indane scaffold, which is crucial for the development of targeted active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for neurological targets.
• Asymmetric Synthesis Building Block: Utilized in the construction of complex, enantiomerically pure molecules for medicinal chemistry and process development.
• Chemical Research & Development: Serves as a versatile starting material for academic and industrial research into new chemical entities.
• Ligand and Catalyst Development: Potential use in the synthesis of chiral ligands or organocatalysts for asymmetric transformations.

Basic Information

Product Name	(1R)-1-Aminoindane-5-Carbonitrile
CAS No.	903630-06-8
Molecular Formula	C10H10N2
Molecular Weight	158.20 g/mol
Synonyms	(1R)-1-Amino-2,3-dihydro-1H-indene-5-carbonitrile; (R)-1-Aminoindane-5-carbonitrile; 5-Cyano-1-aminoindane (R)-enantiomer; (1R)-5-Cyanoindan-1-amine; (R)-1-Amino-5-cyanoindane; 1H-Indene-5-carbonitrile, 1-amino-2,3-dihydro-, (1R)-; (R)-AICN
EINECS	Contact for details

Quality Control

Our (1R)-1-Aminoindane-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.