Description

n-(1-(5-Chloro-2,3-Dimethoxyphenyl)Ethyl)-5-Fluoro-2-(Methylsulfonyl)Benzenamine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it offers a critical building block for research and development in medicinal chemistry, enabling the creation of novel therapeutic agents. It is primarily needed by pharmaceutical manufacturers, biotechnology R&D labs, and fine chemical synthesis companies focused on developing new drug candidates, particularly in areas requiring sophisticated sulfonamide and fluorinated aromatic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Medicinal Chemistry Research: Used in drug discovery and development for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Synthesis: Serves as a precursor for creating more complex sulfonamide and fluorinated aromatic compounds in custom synthesis projects.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays and proteomics research due to its specific structural motifs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	n-(1-(5-Chloro-2,3-Dimethoxyphenyl)Ethyl)-5-Fluoro-2-(Methylsulfonyl)Benzenamine
CAS No.	903581-02-2
Molecular Formula	C17H19ClFNO4S
Molecular Weight	387.85 g/mol
Synonyms	5-Fluoro-2-(methylsulfonyl)-N-[1-(5-chloro-2,3-dimethoxyphenyl)ethyl]aniline; Benzenamine, N-[1-(5-chloro-2,3-dimethoxyphenyl)ethyl]-5-fluoro-2-(methylsulfonyl)-; 903581-02-2; N-(1-(5-Chloro-2,3-dimethoxyphenyl)ethyl)-5-fluoro-2-(methylsulfonyl)aniline; 5-Fluoro-2-methylsulfonyl-N-[1-(5-chloro-2,3-dimethoxyphenyl)ethyl]benzenamine
EINECS	Contact for details

Quality Control

Our n-(1-(5-Chloro-2,3-Dimethoxyphenyl)Ethyl)-5-Fluoro-2-(Methylsulfonyl)Benzenamine is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with batch-specific data are available upon request. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.