Description

(S)-tert-Butyl (5-Cyano-2,3-Dihydro-1H-Inden-1-Yl)Carbamate is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its core value lies in its role as a key building block for constructing complex, biologically active molecules with defined stereochemistry. This compound is essential for research and development chemists and production teams in the pharmaceutical and fine chemical industries, particularly those focused on developing novel therapeutics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• API Development: Used as a key building block in the research and scale-up production of Active Pharmaceutical Ingredients (APIs) requiring a defined (S)-configuration.
• Asymmetric Synthesis: Serves as a versatile starting material or intermediate in asymmetric synthesis protocols to introduce the indane scaffold with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for advanced material science and agrochemical applications.
• Process Chemistry: Integrated into optimized manufacturing routes for the cost-effective and scalable production of target molecules.

Basic Information

Product Name	(S)-tert-Butyl (5-Cyano-2,3-Dihydro-1H-Inden-1-Yl)Carbamate
CAS No.	903557-33-5
Molecular Formula	C15H18N2O2
Molecular Weight	258.32 g/mol
Synonyms	(1S)-1-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,3-dihydro-5-cyano-1H-indene; (S)-1-((tert-Butoxycarbonyl)amino)-5-cyano-2,3-dihydro-1H-indene; (S)-tert-Butyl (5-cyano-2,3-dihydro-1H-inden-1-yl)carbamate; (S)-Boc-1-amino-5-cyanoindane; 1H-Indene-1-carboxamide, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-2,3-dihydro-5-cyano-, (1S)-; (S)-5-Cyano-1-indanyl N-Boc-carbamate
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl (5-Cyano-2,3-Dihydro-1H-Inden-1-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.