Description

tert-Butyl (5-Bromo-2,3-Dihydro-1H-Inden-1-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a brominated indane core protected by a Boc (tert-butoxycarbonyl) group. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, enabling precise molecular construction. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine substituent, facilitating the introduction of the indane scaffold into more complex structures.
• Protease Inhibitor Research: Serves as a core structural element in the research and development of protease inhibitors, leveraging the indane moiety.
• Agrochemical Active Ingredient Development: Used in creating new generations of herbicides, fungicides, and insecticides that require specific, complex heterocyclic frameworks.
• Material Science Research: Employed in the development of organic semiconductors, ligands for catalysis, and other functional organic materials.

Basic Information

Product Name	tert-Butyl (5-Bromo-2,3-Dihydro-1H-Inden-1-Yl)Carbamate
CAS No.	903555-95-3
Molecular Formula	C14H18BrNO2
Molecular Weight	312.20 g/mol
Synonyms	1-N-Boc-5-bromoindane; 5-Bromo-1-indanyl N-Boc amine; tert-Butyl 5-bromo-2,3-dihydro-1H-inden-1-ylcarbamate; 5-Bromo-2,3-dihydro-1H-inden-1-amine, N-[(1,1-dimethylethoxy)carbonyl]-; Boc-5-bromoindanylamine; N-Boc-5-bromoindan-1-amine; 5-Bromo-N-Boc-1-aminoindane; 903555-95-3
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Bromo-2,3-Dihydro-1H-Inden-1-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent quality suitable for research and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.