Description

2-(tert-Butoxycarbonylamino)Pyridin-4-Ylboronic Acid CAS NO 903513-59-7 is a high-purity, advanced pharmaceutical intermediate belonging to the class of pyridinylboronic acids. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules through efficient cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between the pyridine ring and various aryl or vinyl halides, essential for constructing complex heterocyclic scaffolds.
• Pharmaceutical Research & Development (R&D): Serves as a versatile building block in the discovery and synthesis of new drug candidates, particularly in oncology, neurology, and anti-infective therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the process development and commercial-scale manufacturing of APIs that incorporate a functionalized pyridine moiety.
• Agrochemical Intermediate: Employed in the synthesis of advanced crop protection agents and herbicides that require specific pyridine-based structures.
• Material Science & Organic Electronics: Acts as a precursor for creating functional organic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Useful in the design and synthesis of molecular probes and inhibitors for studying biological pathways and protein function.

Basic Information

Product Name	2-(tert-Butoxycarbonylamino)Pyridin-4-Ylboronic Acid
CAS No.	903513-59-7
Molecular Formula	C10H15BN2O4
Molecular Weight	238.05 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)pyridin-4-ylboronic acid; 2-(Boc-amino)-4-pyridinylboronic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine, N-Boc protected; 2-(tert-Butoxycarbonylamino)-4-pyridinylboronic acid; 2-(N-Boc-amino)-4-pyridylboronic acid; Boc-2-amino-4-pyridinylboronic acid; 2-(tert-Butoxycarbonylamino)-4-pyridylboronic acid; 2-(Boc-NH)-4-PyBor
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonylamino)Pyridin-4-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and REACH standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.