Description

D-Threo-1-(4-Sulfonylphenyl)-2-Dichloroacetylamino-1,3-Propanediol Sodium Salt is a high-purity, synthetically derived chemical intermediate of significant importance in advanced pharmaceutical research and development. Its unique molecular structure, featuring a dichloroacetyl-protected amino group and a sulfonylphenyl moiety, makes it a critical building block for the synthesis of complex, biologically active molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex small-molecule drugs.
• Protease Inhibitor Research: Serves as a precursor or core structure in the synthesis of compounds targeting various protease enzymes.
• Antiviral Drug Development: Used in the synthetic pathways for investigational antiviral agents, leveraging its specific stereochemistry.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Process Chemistry & Scale-Up: Acts as a defined starting material or intermediate in the optimization and pilot-scale production of candidate drugs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Item	Details
Product Name	D-Threo-1-(4-Sulfonylphenyl)-2-Dichloroacetylamino-1,3-Propanediol Sodium Salt
CAS No.	903508-30-5
Molecular Formula	C11H11Cl2NNaO6S
Molecular Weight	390.17 g/mol
Synonyms	Sodium D-threo-1-(4-sulfonylphenyl)-2-dichloroacetamido-1,3-propanediol; 1,3-Propanediol, 1-(4-sulfonylphenyl)-2-(dichloroacetamido)-, sodium salt, D-threo-; D-Threo-1-(p-Sulfonylphenyl)-2-dichloroacetamido-1,3-propanediol Sodium Salt; (2R,3S)-1-(4-Sulfonylphenyl)-2-(2,2-dichloroacetamido)-1,3-propanediol Sodium Salt; 903508-30-5 (CAS Registry Number); Dichloroacetyl-protected sulfonylphenyl amino diol sodium salt
EINECS	Contact for details

Quality Control

Our D-Threo-1-(4-Sulfonylphenyl)-2-Dichloroacetylamino-1,3-Propanediol Sodium Salt is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profile. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (D-Threo isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.