Description

7-(tert-Butoxycarbonyl)-3-Chloro-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-2-Carboxylic Acid CAS NO 903130-30-3 is a high-purity, advanced pharmaceutical intermediate featuring a protected imidazopyrazine scaffold. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Used in the construction of heterocyclic cores found in potential kinase inhibitor candidates for oncology and inflammatory diseases.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity chemical building blocks.
• Process Chemistry & Scale-Up: Employed in route scouting and process development to establish robust, scalable synthetic pathways for clinical and commercial API manufacturing.

Basic Information

Product Name	7-(tert-Butoxycarbonyl)-3-Chloro-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-2-Carboxylic Acid
CAS No.	903130-30-3
Molecular Formula	C₁₂H₁₆ClN₃O₄
Molecular Weight	301.73 g/mol
Synonyms	3-Chloro-7-[(2-methylpropan-2-yl)oxycarbonyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid; 3-Chloro-7-Boc-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid; 7-Boc-3-chloro-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylic acid; tert-Butyl 3-chloro-2-(carboxy)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate; Boc-protected 3-chloroimidazopyrazine carboxylic acid; CAS 903130-30-3
EINECS	Contact for details

Quality Control

Our 7-(tert-Butoxycarbonyl)-3-Chloro-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.