Description

4-(Piperidin-3-Yloxy)-Benzonitrile is a versatile and high-value pharmaceutical intermediate featuring a benzonitrile core linked to a piperidine moiety via an ether bridge. This molecular architecture makes it a critical building block for the synthesis of complex active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research & Development: Serves as a standard or reagent in academic and industrial R&D labs for exploring new synthetic pathways.
• API Manufacturing: Employed in the scaled-up production of specific active pharmaceutical ingredients requiring its unique structural motif.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Item	Details
Product Name	4-(Piperidin-3-Yloxy)-Benzonitrile
CAS No.	902837-34-7
Molecular Formula	C12H14N2O
Molecular Weight	202.25 g/mol
Synonyms	4-(3-Piperidyloxy)benzonitrile; 4-(Piperidin-3-yloxy)benzonitrile; Benzonitrile, 4-(3-piperidinyloxy)-; 3-(4-Cyanophenoxy)piperidine; 902837-34-7; 4-Piperidin-3-yloxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-(Piperidin-3-Yloxy)-Benzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from techniques such as HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.