Description

n-(6-Piperazin-1-Yl-Pyridazin-3-Yl)-Methanesulfonamide is a high-purity, specialized heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. Its unique molecular structure, featuring a piperazine-linked pyridazine core, makes it a valuable intermediate for synthesizing novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and biotechnology industries. Its consistent quality and reliable supply are essential for accelerating drug discovery timelines and ensuring reproducible results in preclinical studies.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of new therapeutic agents, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe: Used in the design and synthesis of molecular probes to study biological pathways and protein function.
• Process Chemistry Development: Employed in route scouting and scale-up optimization for the commercial manufacturing of candidate drugs.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API production.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and research organizations engaged in custom synthesis projects.

Basic Information

Product Name	n-(6-Piperazin-1-Yl-Pyridazin-3-Yl)-Methanesulfonamide
CAS No.	902836-96-8
Molecular Formula	C9H15N5O2S
Molecular Weight	257.32 g/mol
Synonyms	Methanesulfonamide, N-[6-(1-piperazinyl)-3-pyridazinyl]-; 902836-96-8; N-(6-(piperazin-1-yl)pyridazin-3-yl)methanesulfonamide; 6-(1-Piperazinyl)-3-pyridazinemethanesulfonamide; UNII-4Q8I7O6W2S; 4Q8I7O6W2S; CHEMBL3187612; DTXSID60635660; BDBM50121271
EINECS	Contact for details

Quality Control

Our n-(6-Piperazin-1-Yl-Pyridazin-3-Yl)-Methanesulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.