Description

2-Chloro-4-(3-Piperidinyloxy)Benzonitrile is a high-value, synthetically versatile organic intermediate characterized by its unique benzonitrile core substituted with chloro and piperidinyloxy functional groups. This compound matters for its role as a critical building block in the development of advanced pharmaceutical agents and agrochemicals, enabling precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers engaged in the synthesis of novel bioactive molecules, particularly within medicinal chemistry and crop protection R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in developing novel herbicides and fungicides, leveraging its structural motifs for bioactivity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for further functionalization in organic chemistry, including cross-coupling reactions.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with specific electronic or mechanical properties.
• Contract Research & Development (CRO/CMO): Supplied to service organizations for custom synthesis projects and library generation.

Basic Information

Product Name	2-Chloro-4-(3-Piperidinyloxy)Benzonitrile
CAS No.	902836-92-4
Molecular Formula	C12H13ClN2O
Molecular Weight	236.70 g/mol
Synonyms	2-Chloro-4-(piperidin-3-yloxy)benzonitrile; 4-(3-Piperidyloxy)-2-chlorobenzonitrile; 3-[(4-Cyano-3-chlorophenyl)oxy]piperidine; Benzonitrile, 2-chloro-4-(3-piperidinyloxy)-; 902836-92-4; 2-Chloro-4-(3-piperidinoloxy)benzonitrile; 2-Chloro-4-(3-piperidinoxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3-Piperidinyloxy)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.