Description

3-(4-Chloro-Phenoxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate used in the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical synthesis companies focused on developing new drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacologically active molecules.
• API Synthesis: Integral component in multi-step synthetic routes for producing Active Pharmaceutical Ingredients (APIs).
• Custom Synthesis: Serves as a starting material or intermediate for contract manufacturing and bespoke chemical production.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	3-(4-Chloro-Phenoxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	902836-90-2
Molecular Formula	C16H22ClNO3
Molecular Weight	311.80 g/mol
Synonyms	1-Boc-3-(4-chlorophenoxy)piperidine; tert-Butyl 3-(4-chlorophenoxy)piperidine-1-carboxylate; 3-(4-Chlorophenoxy)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(4-chlorophenoxy)piperidine; N-Boc-3-(4-chlorophenoxy)piperidine; 902836-90-2; 3-(p-Chlorophenoxy)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-Phenoxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.