Description

4-(3-Chlorophenyl)Tetrahydro-2H-Pyran-4-Carboxaldehyde is a versatile and high-purity chemical building block characterized by its aldehyde and chlorinated aromatic functionalities. This compound is critical for research and development in advanced organic synthesis, enabling the creation of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging its chlorophenyl moiety for biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and organic electronic materials due to its rigid molecular structure.
• Custom Synthesis & Contract Manufacturing: A valuable scaffold for custom synthesis projects and scale-up services in fine chemical production.
• Academic & Industrial R&D: Essential for exploratory chemistry in academic institutions and corporate R&D laboratories focusing on heterocyclic chemistry.

Basic Information

Product Name	4-(3-Chlorophenyl)Tetrahydro-2H-Pyran-4-Carboxaldehyde
CAS No.	902836-60-6
Molecular Formula	C12H13ClO2
Molecular Weight	224.68 g/mol
Synonyms	4-(3-Chlorophenyl)tetrahydro-2H-pyran-4-carboxaldehyde; 4-(3-Chlorophenyl)tetrahydropyran-4-carbaldehyde; 3-Chlorophenyl tetrahydropyran-4-yl ketone (related); 4-(3-Chlorophenyl)-4-formyltetrahydropyran; THP-3-chlorophenyl carboxaldehyde; 902836-60-6; 4-(3-Chloro-phenyl)-tetrahydro-pyran-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our production of 4-(3-Chlorophenyl)Tetrahydro-2H-Pyran-4-Carboxaldehyde adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We support cGMP-compliant manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.