Description

1(2H)-Isoquinolinone, 3-[[4-(1,2-Benzisothiazol-3-Yl)-1-Piperazinyl]Carbonyl]- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role in the synthesis of novel bioactive molecules, particularly in central nervous system (CNS) research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new therapeutic agents. The product is supplied with a guaranteed CAS No. 902330-67-0 and adheres to stringent quality control protocols to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential antipsychotic and neuroleptic drug candidates.
• CNS Drug Discovery: Used in medicinal chemistry programs targeting dopamine and serotonin receptor pathways for neurological disorders.
• Biochemical Research: Serves as a reference standard or a precursor in pharmacological studies and assay development.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures with fused ring systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	1(2H)-Isoquinolinone, 3-[[4-(1,2-Benzisothiazol-3-Yl)-1-Piperazinyl]Carbonyl]-
CAS No.	902330-67-0
Molecular Formula	C21H18N4O2S
Molecular Weight	390.46 g/mol
Synonyms	3-[(4-(1,2-Benzothiazol-3-yl)piperazin-1-yl)carbonyl]isoquinolin-1(2H)-one; 3-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]carbonyl]-1(2H)-isoquinolinone; 3-(4-(Benzo[d]isothiazol-3-yl)piperazine-1-carbonyl)isoquinolin-1(2H)-one; BIBO-1 Precursor; CNS Intermediate 902330-67-0; Atypical Antipsychotic Intermediate; 1,2-Benzisothiazole-3-piperazinyl isoquinolinone derivative.
EINECS	Contact for details

Quality Control

Every batch of this pharmaceutical intermediate is produced and analyzed under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, residual solvents, and other critical parameters is provided with each shipment. Our quality commitment aligns with ICH guidelines, and we can support development projects requiring cGMP compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.