Description

5-Chloro-3-{3-[4-(2-Chlorophenyl)-1-Piperazinyl]-3-Oxopropyl}-1,3-Benzoxazol-2(3H)-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key building block for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel central nervous system (CNS) active compounds and potential antipsychotic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates targeting serotonin and dopamine receptors.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for pharmacological studies and the development of new chemical entities.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	5-Chloro-3-{3-[4-(2-Chlorophenyl)-1-Piperazinyl]-3-Oxopropyl}-1,3-Benzoxazol-2(3H)-One
CAS No.	902254-65-3
Molecular Formula	C20H19Cl2N3O3
Molecular Weight	420.29 g/mol
Synonyms	5-Chloro-3-[3-[4-(2-chlorophenyl)piperazin-1-yl]-3-oxopropyl]-1,3-benzoxazol-2-one; 5-Chloro-3-(3-(4-(2-chlorophenyl)piperazin-1-yl)-3-oxopropyl)benzo[d]oxazol-2(3H)-one; 902254-65-3; Benzoxazolone derivative; Aripiprazole intermediate analog; CNS pharmaceutical intermediate
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-{3-[4-(2-Chlorophenyl)-1-Piperazinyl]-3-Oxopropyl}-1,3-Benzoxazol-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.