Description

1-[(2,6-Dimethylphenyl)Methyl]-Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct piperidine-carboxylic acid structure. This compound is critical for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs), offering a versatile building block for drug discovery. It is primarily needed by R&D laboratories, CROs, and pharmaceutical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and analgesic drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs, where its specific stereochemistry and functional groups are essential.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	1-[(2,6-Dimethylphenyl)Methyl]-Piperidine-4-Carboxylic Acid
CAS No.	901923-66-8
Molecular Formula	C16H23NO2
Molecular Weight	261.36 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[(2,6-dimethylphenyl)methyl]-; 1-(2,6-Dimethylbenzyl)piperidine-4-carboxylic acid; 1-[(2,6-Dimethylphenyl)methyl]piperidine-4-carboxylic acid; 1-(2,6-Dimethylbenzyl)-4-piperidinecarboxylic acid; 1-(2,6-Xylylmethyl)piperidine-4-carboxylic acid; 901923-66-8; UNII-9F6L5JX9UQ
EINECS	Contact for details

Quality Control

Our 1-[(2,6-Dimethylphenyl)Methyl]-Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.