Description

1-(3-Ethoxy-Benzyl)-Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the development and validation of robust, scalable synthetic routes under GMP conditions.
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control of final APIs.
• Biochemical Tool Compound: Utilized in pharmacological assays to study specific receptor interactions and signaling pathways.

Basic Information

Product Name	1-(3-Ethoxy-Benzyl)-Piperidine-4-Carboxylic Acid
CAS No.	901920-44-3
Molecular Formula	C16H23NO3
Molecular Weight	277.36 g/mol
Synonyms	1-[(3-Ethoxyphenyl)methyl]piperidine-4-carboxylic acid; 4-Piperidinecarboxylic acid, 1-[(3-ethoxyphenyl)methyl]-; 1-(3-Ethoxybenzyl)piperidine-4-carboxylic acid; 901920-44-3; 1-(3-Ethoxy-benzyl)-piperidine-4-carboxylic acid; 1-(3-Ethoxybenzyl)isonipecotic acid
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Ethoxy-Benzyl)-Piperidine-4-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting regulatory filings from preclinical to commercial stages. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.