Description

2-(3-Fluoro-4-Methoxyphenyl)Piperidine is a high-value fluorinated piperidine derivative, a key structural motif in modern medicinal chemistry. This compound serves as a critical pharmaceutical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted drug discovery. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking to build complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Ligand Synthesis: Key precursor for creating selective ligands for various receptors (e.g., sigma, dopamine, serotonin receptors).
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for API manufacturing.
• Chemical Biology Probes: Useful for developing tool compounds to study biological pathways and protein function.
• Fine Chemical Synthesis: Serves as a specialized intermediate for synthesizing other complex fluorinated aromatic compounds.

Basic Information

Product Name	2-(3-Fluoro-4-Methoxyphenyl)Piperidine
CAS No.	901917-84-8
Molecular Formula	C12H16FNO
Molecular Weight	209.26 g/mol
Synonyms	2-(3-Fluoro-4-methoxyphenyl)piperidine; 1-(3-Fluoro-4-methoxyphenyl)-2-piperidine; 3-Fluoro-4-methoxy-2-piperidinylbenzene; Piperidine, 2-(3-fluoro-4-methoxyphenyl)-; 901917-84-8; 2-(3-Fluoro-4-methoxyphenyl)piperidine hydrochloride (salt form); 2-(3-Fluoro-4-methoxyphenyl)piperidine HBr (salt form)
EINECS	Contact for details

Quality Control

Our 2-(3-Fluoro-4-Methoxyphenyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent quality suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.