Description

1,3,5-Trimethyl-2,4-Dioxo-1,2,3,4-Tetrahydro-Pyrido[2,3-D]Pyrimidine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting specific enzymatic pathways.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities (NCEs).
• API Synthesis: Serves as a core scaffold for constructing active pharmaceutical ingredients with potential antiviral, anticancer, or neurological activity.
• Biochemical Research: Employed as a standard or reagent in biochemical assays to study protein-ligand interactions.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	1,3,5-Trimethyl-2,4-Dioxo-1,2,3,4-Tetrahydro-Pyrido[2,3-D]Pyrimidine-7-Carboxylic Acid
CAS No.	901864-90-2
Molecular Formula	C12H11N3O4
Molecular Weight	261.24 g/mol
Synonyms	7-Carboxy-1,3,5-trimethyl-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-2,4-dione; 1,3,5-Trimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-7-carboxylic acid; Pyrido[2,3-d]pyrimidine-7-carboxylic acid, 1,2,3,4-tetrahydro-1,3,5-trimethyl-2,4-dioxo-; 1,3,5-Trimethyl-2,4-dioxo-1,4-dihydropyrido[2,3-d]pyrimidine-7-carboxylic acid; CAS 901864-90-2
EINECS	Contact for details

Quality Control

Our 1,3,5-Trimethyl-2,4-Dioxo-1,2,3,4-Tetrahydro-Pyrido[2,3-D]Pyrimidine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and relevant pharmacopeial guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.