Description

n-(1,1-Dioxidotetrahydro-3-Thienyl)-n-{[5-(4-Fluorophenyl)-2-Furyl]Methyl}-2-Propoxybenzamide is a high-purity, non-racemic synthetic organic compound of significant interest in advanced pharmaceutical research and development. This complex molecule serves as a critical intermediate or active pharmaceutical ingredient (API) for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and production of new drugs, particularly those targeting specific neurological or metabolic pathways. The compound, identified by CAS number 901659-81-2, demands stringent quality control to ensure consistency and efficacy in downstream applications.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Active Pharmaceutical Ingredient (API) Development: Serves as the core active moiety for investigational new drugs (INDs) undergoing preclinical and clinical trials.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate receptor binding and enzyme inhibition.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.
• Academic Research: Employed in university and institutional labs for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Process Chemistry: Utilized in route scouting and optimization for scalable and cost-effective manufacturing processes.

Basic Information

Product Name	n-(1,1-Dioxidotetrahydro-3-Thienyl)-n-{[5-(4-Fluorophenyl)-2-Furyl]Methyl}-2-Propoxybenzamide
CAS No.	901659-81-2
Molecular Formula	C25H26FNO5S
Molecular Weight	471.54 g/mol
Synonyms	2-Propoxy-N-[(5-(4-fluorophenyl)-2-furyl)methyl]-N-(tetrahydro-1,1-dioxido-3-thienyl)benzamide; N-[(5-(4-Fluorophenyl)-2-furanyl)methyl]-N-(1,1-dioxido-3-thiolanyl)-2-propoxybenzamide; 901659-81-2; Benzamide, N-[(5-(4-fluorophenyl)-2-furanyl)methyl]-N-(tetrahydro-1,1-dioxido-3-thienyl)-2-propoxy-; (R)- or (S)-enantiomer forms may be available.
EINECS	Contact for details

Quality Control

Our n-(1,1-Dioxidotetrahydro-3-Thienyl)-n-{[5-(4-Fluorophenyl)-2-Furyl]Methyl}-2-Propoxybenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with ICH guidelines, and we can support development toward cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee (specify enantiomer)
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.