Description

3-{3-[4-(2,3-Dimethylphenyl)-1-Piperazinyl]-3-Oxopropyl}-4(3H)-Quinazolinone is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is critical for medicinal chemists seeking to develop novel therapeutic agents targeting central nervous system (CNS) disorders and other complex diseases. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of lead compounds.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns.
• Preclinical Development: Serves as a critical material for producing batches required for pharmacological and toxicological evaluation.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic pathways and heterocyclic chemistry.
• Contract Manufacturing: Supplied to CDMOs for the scale-up and cGMP production of active pharmaceutical ingredients (APIs) under development.

Basic Information

Product Name	3-{3-[4-(2,3-Dimethylphenyl)-1-Piperazinyl]-3-Oxopropyl}-4(3H)-Quinazolinone
CAS No.	900892-51-5
Molecular Formula	C23H26N4O2
Molecular Weight	390.48 g/mol
Synonyms	3-[3-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-3-oxopropyl]quinazolin-4-one; 4(3H)-Quinazolinone, 3-[3-[4-(2,3-dimethylphenyl)-1-piperazinyl]-3-oxopropyl]-; 900892-51-5; UNII-6K4V8YVW1F; 6K4V8YVW1F; 3-(3-{4-[(2,3-Dimethylphenyl)]piperazin-1-yl}-3-oxopropyl)-4(3H)-quinazolinone; 3-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-3-oxopropyl)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 3-{3-[4-(2,3-Dimethylphenyl)-1-Piperazinyl]-3-Oxopropyl}-4(3H)-Quinazolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.