Description

(3S,5S)-5-((1S,3S)-1-Amino-3-(4-Methoxy-3-(3-Methoxypropoxy)Benzyl)-4-Methylpentyl)-3-Isopropyldihydrofuran-2(3H)-One is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is of critical importance for its role in the synthesis of complex active pharmaceutical ingredients (APIs), where precise chirality is essential for biological activity. It is primarily needed by pharmaceutical R&D laboratories and manufacturers specializing in the production of sophisticated, small-molecule therapeutics.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block in the multi-step synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Chiral Building Block Production: Used for constructing complex molecular architectures where specific stereocenters are required for drug efficacy and safety profiles.
• Pharmaceutical Process Development: Employed in route scouting, optimization, and scale-up activities from laboratory to pilot plant and commercial manufacturing.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under GMP (Good Manufacturing Practice) guidelines.
• Academic & Industrial Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and the discovery of new biological entities.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	(3S,5S)-5-((1S,3S)-1-Amino-3-(4-Methoxy-3-(3-Methoxypropoxy)Benzyl)-4-Methylpentyl)-3-Isopropyldihydrofuran-2(3H)-One
CAS No.	900811-48-5
Molecular Formula	C25H41NO5
Molecular Weight	435.60 g/mol
Synonyms	5-[(1S,3S)-1-Amino-3-[4-methoxy-3-(3-methoxypropoxy)phenyl]-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one; (3S,5S)-5-((1S,3S)-1-Amino-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyldihydrofuran-2(3H)-one; UNII-9Q1V8V8A0N; 9Q1V8V8A0N; (3S,5S)-5-[(1S,3S)-1-Amino-3-[4-methoxy-3-(3-methoxypropoxy)phenyl]-4-methylpentyl]-3-(1-methylethyl)-2(3H)-furanone; (3S,5S)-5-((1S,3S)-1-Amino-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentyl)-3-isopropyl-2,3-dihydrofuran-2-one
EINECS	Contact for details

Quality Control

Our (3S,5S)-5-((1S,3S)-1-Amino-3-(4-Methoxy-3-(3-Methoxypropoxy)Benzyl)-4-Methylpentyl)-3-Isopropyldihydrofuran-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment. We can support development projects with material produced under ICH Q7 compliant conditions for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.