Description

(αs,γs)-4-Methoxy-3-(3-Methoxypropoxy)-γ-(1-Methylethyl)-α-[[(Phenylmethoxy)Carbonyl]Amino]Benzenepentanoic Acid is a sophisticated chiral organic compound designed for advanced chemical synthesis. This molecule is of significant value in pharmaceutical research and development, serving as a critical building block or advanced intermediate for novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors working on complex therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Process Chemistry Research: Used in route scouting and optimization studies to develop efficient, scalable manufacturing processes for target molecules.
• Asymmetric Synthesis: Employed in reactions requiring high stereochemical control due to its defined (αs,γs) configuration, enabling the construction of complex stereocenters.
• Peptidomimetic & Prodrug Development: The structural features, including the protected amino acid moiety, make it suitable for designing peptide-like molecules and prodrug constructs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Custom Synthesis Starting Material: Provides a versatile core structure for contract research organizations (CROs) and CDMOs to build custom molecules for client projects.

Basic Information

Product Name	(αs,γs)-4-Methoxy-3-(3-Methoxypropoxy)-γ-(1-Methylethyl)-α-[[(Phenylmethoxy)Carbonyl]Amino]Benzenepentanoic Acid
CAS No.	900811-41-8
Molecular Formula	C27H35NO7
Molecular Weight	485.57 g/mol
Synonyms	(2S,4S)-4-Methoxy-3-(3-methoxypropoxy)-2-[(benzyloxycarbonyl)amino]-5-methylhexanoic Acid; (2S,4S)-2-[(Benzyloxycarbonyl)amino]-4-methoxy-3-(3-methoxypropoxy)-5-methylhexanoic Acid; (2S,4S)-N-Cbz-4-methoxy-3-(3-methoxypropoxy)-5-methyl-2-aminopentanoic Acid; Cbz-(2S,4S)-4-Methoxy-3-(3-methoxypropoxy)-5-methyl-2-aminopentanoic Acid; (αs,γs)-N-Cbz-4-Methoxy-3-(3-Methoxypropoxy)-5-Methyl-2-aminopentanoic Acid; 900811-41-8; Benzenepentanoic acid, 4-methoxy-3-(3-methoxypropoxy)-γ-(1-methylethyl)-α-[[(phenylmethoxy)carbonyl]amino]-, (αS,γS)-
EINECS	Contact for details

Quality Control

Our (αs,γs)-4-Methoxy-3-(3-Methoxypropoxy)-γ-(1-Methylethyl)-α-[[(Phenylmethoxy)Carbonyl]Amino]Benzenepentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess and standard spectroscopic methods for identity confirmation, to ensure high chemical and chiral purity suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.